Developed by Zhu, et al [2011]: Optofluorescent imaging cytometry on a cell phone, Anal. Chem., 2011, 83 (17), pp 6641-6647 (technology being marketed by Holomic LLC)
Zhu et al 2013, Cost-effective and rapid blood analysis on a cell-phone, http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594636/
Imaging flow cytometer
Low-cost materials
Phone provides camera, potential image processing capability
Spatial resolution: ~2 micron
Paper contains fairly detailed description of materials, design
Select filters and LED for target cell type
Image processing performed on laptop computer when this paper was published, algorithms implemented in OpenCV. Note that Android has OpenCV implementation.
Throughput largely limited by camera frame rate. Frame rate of 120 fps could result in whole-blood imaging time of 20 seconds.
Also see CellScope work, from Fletcher lab at UC Berkeley: http://cellscope.berkeley.edu/
Zhu Flow Cytometry on a Cell Phone ACHEM2011.pdf (application/pdf)
figure.jpg (image/jpeg)
Mao Microfluidic diagnostics for the developing world 2012.pdf (application/pdf)
